Lesson 3: Causes of Autoimmunity

what causes autoimmunity?

According to research

  • Genetics
  • Endogenous Factors
  • Environmental


For autoimmunity to express, researchers believe there must be a genetic predisposition. While we can not do anything about our genetics, research suggests that genetics alone is not enough, there must be a trigger that turns the genes on. Triggers can be internal such as stress or hormone imbalance. Or environmental such as exposure to toxins or viruses.

Endogenous Factors

Endogenous means having an internal cause or origin. Examples of endogenous factors are aging, intestinal permeability (aka…leaky gut), and endocrine changes such as those that occurring during pregnancy, postpartum, and menopause.

Environmental Factors

  • Endocrine disrupting toxins (household, beauty care and food)
  • Infections (viral or bacterial)
  • Stress (prolonged stress)
  • Trauma (even childhood!)
  • Certain medications